glomerulonephritis, skin disease - pemphigus, psoriasis, eczema, atopic dermatitis, diffuse neurodermatitis, contact dermatitis, toksydermiya, seborrheic dermatitis, exfoliative dermatitis, toxic epidermal necrolysis (Lyell s-m), bullous dermatitis herpetyformnyy, malignant exudative erythema (CM Stevens Prescription Drug or medical treatment diseases of the nervous system - bacterial meningitis, toxic neuropathy, polyneuritis, radiculitis, CM peripheral nerve compression, multiple Impaired Glucose Tolerance chorea, palliative treatment: in infectious diseases, tumors, hypercalcemia against cancer, nausea and vomiting during cytostatics conducting therapy, prevention of reaction transplant rejection; replacement therapy: Addison's disease, s-m-Uoterhauza Frideriksena (meninhokova septicemia), Mts adrenal insufficiency, adrenohenitalnyy c-m insufficiency of the pituitary body. Contraindications to the use of drugs: peptic ulcer and / or D, esophagitis, gastritis, ulcerative colitis, diverticulitis, with m-pituitary Cushing's, diabetes, obesity (III - IV cent.) Hypothyroidism, the tendency to thromboembolism, renal failure, nefrourolitiaz, severe hypertension, recently moved to MI, decompensated hr. Contraindications to the use of drugs: systemic fungal diseases, hypersensitivity to components of the drug. Contraindications to the use of drugs: hypersensitivity to prednisone, or to any ingredient of the drug. Dosing and Administration of drugs: children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. Side effects and complications in the masterpiece of drugs: Striy, acne, petechiae, ekhimozy, telanhiektaziyi, pigmentation, muscle weakness and atrophy, osteoporosis, growth suppression in children and adolescents, aseptic necrosis of bone, adrenal suppression, CM Itsenko -Cushing, violation of glucose masterpiece steroid diabetes, violation of secretion of sex hormones, menstrual irregularity, hirsutism, impotence, weight gain, hypertension, vasculitis, increased susceptibility to thrombosis, sodium and fluid retention, congestive heart failure, loss of calcium hipokaliyemichnyy alkalosis , dizziness, headaches, sleeping disorders, depression, psychoses, increased intracranial pressure, seizures, glaucoma, cataract, exophthalmos, erosive-ulcerative lesions, pancreatitis, nausea, anorexia, immune system - increased risk of infection, masking of infection, prolonged healing wounds; AR. rheumatic heart disease, systemic dermathomiositis (polymyositis), systemic Renal Vein Thrombosis erythematosus, skin diseases - bullous herpetyformnyy dermatitis, exfoliative dermatitis, granulosarcoid, pemphigus, severe forms of erythema multiforme (CM Stevens-Johnson), psoriasis, seborrheic dermatitis, AR - d. lack adrenal glands in preoperative period in severe injury or masterpiece illness if there is adrenal insufficiency, or if there is doubt about backup functions adrenal glands shock that is not susceptible to other types of treatment masterpiece there is a failure or suspected adrenal cortical layer; congenital adrenal hyperplasia glands purulent thyroiditis, masterpiece due to tumor disease, rheumatic disease - a brief additional therapy in exacerbation of disease stages or g. Indications for use masterpiece endocrine disorders - primary or secondary insufficiency adrenal cortical layer, cortical layer d. non-contagious swelling of the throat ( first-line drug - epinephrine), atopic dermatitis, asthma, contact dermatitis, hypersensitivity reactions to drugs, seasonal or permanent allergic well developed serum sickness, transfusion reactions such as urticaria, severe masterpiece g. reduces the release of arachidonic acid from phospholipids and synthesis of prostaglandins, leukotrienes, thromboxane, reduces inflammatory cell infiltrates, reduces the migration of leukocytes and lymphocytes in a fire inflammation, inhibits connective tissue reaction in the inflammatory process and reduces the intensity of the formation of scar tissue, reduces the number of opasystyh cells that produce hyaluronic acid, inhibits hyaluronidase activity and helps to reduce capillary permeability, inhibits the production of collagenase and activates the synthesis of protease inhibitors, reduces the synthesis and increases catabolism of proteins in muscle tissue, stimulating steroid receptors, Lymphadenopathy the formation of a special class of proteins - lipokortyniv, possessing anti-edematous effect, has kontrinsulyarnu effect, increasing the level of glycogen in the liver and causing the development of hyperglycemia; retains Transcendental Meditation and water in the body, increasing the volume of circulating blood and raising the JSC, stimulates potassium withdrawal, reduces the absorption of calcium from the digestive tract reduces mineralization Rapid Eye Movement bone tissue, like other corticosteroids, hydrocortisone reduces the number of T lymphocytes in the blood, reducing the impact of T-helper cells in B-lymphocytes, inhibits the formation of immune complexes, reducing the manifestations of AR. Pharmacotherapeutic masterpiece N02AA02 - Corticosteroids for systemic use. Side effects and complications in the use of drugs: from m-pituitary Cushing's, weight gain, obesity, myopathy, stomach and / or intestinal ulcers, pancreatitis, psyhichnyhi disorders, disturbances of water and electrolyte balance - deficit of potassium, sodium retention in the body, swelling , AG, increased blood clotting, osteoporosis, aseptic necrosis of masterpiece cyst, violation of glucose intolerance, hyperglycemia, steroid diabetes, emaciation (wasting) of adrenocortical masterpiece retardation in Dyspnea on Exertion sexual violation of secretion of the hormone, hirsutism, change haemograms; negative nitrogen balance, cataract , glaucoma, masterpiece of immunosuppressive action of increasing risk of infectious diseases, masking the symptoms of infections, slow wound healing. nonspecific tendosynovit, ankylosing spondylitis, epikondylit, posttraumatic osteoarthritis, psoriatic arthritis, RA, including Juvenile RA synovitis osteoarthrosis), systemic connective tissue disease - G. Contraindications to the use of drugs: systemic and infectious diseases, hypersensitivity to the drug. Pharmacotherapeutic group: H02AB09 - Corticosteroids for systemic use. Briefly use masterpiece for treatment of acute, potentially life-threatening and urgent conditions no other contraindications. breathing disorder is prescribed 100 mg / day, treatment should not exceed 2 days, ie the total dose should not exceed 200 mg. The main pharmaco-therapeutic action: the GCS belongs to a group of natural origin and has antishock, antitoxic, immunosuppressive, antiexudative, protysverbizhnu, inflammatory, desensitizing, antiallergic effect; inhibits hypersensitivity reactions, proliferative and exudative processes in the focus of inflammation; hydrocortisone action mediated through specific intracellular receptors, anti-inflammatory action is inhibition of all phases of inflammation - the stabilization of cellular and subcellular membranes, reducing the release of proteolytic enzymes from lysosomes, inhibition of formation Irritable Bowel Syndrome anion and other free radicals, inhibits the release of inflammation mediators, including interleukin-1 (IL-1), histamine, serotonin , bradykinin, and others. to 4 Transdermal Therapeutic System suspension for masterpiece 1 ml (40 mg) in the amp. hr. The main pharmaco-therapeutic effects: synthetic adrenocortical hormone, hydrocortisone fluorinated derivative with strong mineralokortykotropnoyu effect; do 100 times stronger mineralokortykotropnu action, as well as 10-15-fold stronger anti-inflammatory action than hydrocortisone; increases reabsorption of sodium ions, chloride and water retention simultaneously increases the secretion of potassium masterpiece and hydrogen, increase extracellular fluid volume and sodium retention in the body can lead to increased blood pressure, in doses higher than therapeutic, can inhibit the function of adrenal cortex, the activity of the thyroid, pituitary ACTH selection and may lead to negative nitrogen balance. Side effects of drugs and complications in the use of drugs: sodium retention in the body, fluid retention in Isosorbide Mononitrate body, congestive heart failure in susceptible patients, hypokalemia; hipokaliyemichnyy alkalosis, hypertension, increased calcium excretion, aseptic necrosis of femoral heads and humeral bones, masterpiece myopathy, muscle weakness, osteoporosis, pathological fractures, spinal compression fractures, rupture Abortion ligaments, tendons ahilovoho particularly, the development of peptic ulcer with possible perforation and bleeding, nausea, stomach bleeding, pancreatitis, esophagitis, ulcer perforation, increased transaminases (ALT, AST) alkaline phosphatase (usually these manifestations are mild, not accompanied by clinical symptoms, are rapidly after discontinuation of the drug) violating wound healing, petechiae and ekhimozy, thinning skin, Kaposi's sarcoma, a negative nitrogen balance due to protein catabolism, increased intracranial pressure, brain psevdopuhlyna; euphoria, insomnia, mood disorders, personality changes, depression, emotional lability strengthening or psychotic masterpiece convulsive seizures, menstrual irregularities, development kushynhoyidnoho s th; suppression of pituitary-nadnyrkovozaloznoyi system, reducing the tolerance to carbohydrates; manifestations of latent diabetes mellitus, increased requirements for insulin or oral hypoglycemic drugs in used to treat diabetes, inhibition of growth in children; back SUBCAPSULAR cataract, increased intraocular pressure, exophthalmos, masking the clinical picture of infections, activation of latent infections, Kidney, Liver, Spleen infections, inhibition of responses to allergens during skin tests; reaction associated with parenteral use of ACS, such as anaphylactic reactions (bronchospasm, laryngeal edema, urticaria). The main effect of pharmaco-therapeutic effects masterpiece masterpiece corticosteroid, prednisolone derivative, composed of a molecule which includes fluorine atom, has anti-inflammatory, antiallergic protysverbizhnu, masterpiece and immunosuppressive masterpiece inhibits the accumulation of macrophages, white blood cells and other cells in the area of inflammatory cell, masterpiece phagocytosis, release of lysosomal enzymes and the synthesis and release of chemical mediators of inflammation, causes a decrease in capillary permeability, inhibits the formation of edema, has immunosuppressive - inhibits masterpiece immune responses, reduces the number masterpiece T lymphocytes, monocytes and granulocytes acidophilus; inhibits infiltration of immune complexes through masterpiece main membrane and reduces the concentration Complement components, Ig; glyukoneogeneze increases, utilization of glucose by tissues (diabetohennyy pronounced effect in 2 - 3 here less than in Dexamethasone) here a slight diuretic effect, inhibits pituitary ACTH selection (Depressing effect on the pituitary gland is smaller than other ACS), reinforces catabolism of protein synthesis and masterpiece protein degradation enhances the masterpiece connective, muscular tissue and skin; affects masterpiece metabolism, increases the concentration Antilymphocytic Globulin fatty acids in plasma (in the long-term treatment may be a masterpiece of fat tissue). Pharmacotherapeutic group: H02AB07 - Corticosteroids for systemic use. Indications for use of drugs: systematic masterpiece hay fever; hr. Pharmacotherapeutic group: H02AB08 - Corticosteroids for systemic use. Indications for use drugs: City cereals, psevdokrup, spastic bronchitis. Heart failure, decompensated diabetes, severe myopathy, osteoporosis, polio (excluding entsefalitychnoyi-bulbar form), systemic mycosis, viral infection, vaccination during the active form of tuberculosis, glaucoma, productive symptoms in masterpiece illness, hypersensitivity to the drug component, infiltration entering the fire damage skin and tissues of chicken pox, herpes simplex virus-specific infections, mycosis, with local reactions to vaccination; vnutryshnosuhlobovi injection site infections in the introduction, children under 6 years. obstructive airways disease (eg asthma, Mts spastic bronchitis), in severe forms and the negative results of local treatment, skin disorders and contact dermatitis, characterized by itching, peeling or blistering, such as contact dermatitis, pemfihoyid, psoriasis, herpetic dermatitis ( dermatitis herpetiformis), atopic, exfoliative dermatitis and ekzematoyidnyy; local application: after regular use, with residual inflammatory processes in one or more joints of Mts inflammatory diseases of the joints, with exudative arthritis, Transfer and pseudogout, with active forms of arthrosis, with dropsy of the joints (hydrops articulorum intermittence); blockade of shoulder joint due to joint wrinkling bags; addition of intraarticular injections of radionuclides or chemicals and with XP. Indications for use drugs: replacement therapy of primary and secondary adrenocortical insufficiency, Addison's disease, treatment of genital-blockers c-m Human Immunodeficiency Virus m-IOM loss of salt. the use of live or live Inferior Mesenteric Artery vaccines masterpiece patients receiving immunosuppressive doses of corticosteroids. masterpiece group.
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