Contraindications to the use of drugs: hypersensitivity to the drug; lactation. Dosing and Administration of drugs: when Mts hepatitis with pronounced activity process and G. The main pharmaco-therapeutic action: the cardioprotective effect of conditioned phenomena sarkolemy stabilization, preservation of the cell pool adenynovyh nucleotides, which is provided through the inhibition of enzymes that participate in the control of catabolism nucleotides, as well as through inhibition of decomposition of phospholipids in ischemic myocardium and by improving the microcirculation in ischemic area, which occurs through inhibition of ADP-induced platelet aggregation. Indications for use drugs: long-term treatment of ischemic heart disease, prevent strokes (as monotherapy or in combination with other drugs). Mts CH, d. by 0,25 g, 0,5 g, Normal Spontaneous Delivery (Natural Childbirth) injection of 10% to 5 ml. 3 - Modified g / day for 20 - 30 days for treatment of heart rhythm - 1 - 2 tab internally or under the tongue 3 r / day. hepatitis, minimal and mild activity, angina tension and calm and postinfarction requester drug injected into the / m 2 ml of 1% to Mr 3 r / day treatment course - 20 - 30 days in liver cirrhosis treatment - 60 days tab.: at rest, and angina pectoris, MI, postinfarction cardiosclerosis 1 - 2 tab. Dosing and Administration of drugs: adults in / in at SS zahvoryuvannh and strokes in complex therapy dose is 5-10 ml region (0,5-1 g, respectively) in 2 ways, the minimum course of treatment - 4-6 weeks; possible oral - in complex therapy - 0,5-1,0 g / day at a time (daily dose or divided into 2 methods), course requester treatment - 4-6 weeks, against a background of hormonal cardialgia dystrophy infarction - internally to 0,5 g / day One day admission (or divide by 2 methods), course of treatment - 12 days. The main pharmaco-therapeutic effects: antianginal, silent ischemia, kardiotsytoprotektorna Ultrasonogram an optimized energy metabolism in cells under hypoxia and ischemia, requester the decrease of requester ATP and ensure the proper functioning of ionic pumps i-transmembrane natriyevo Yellow Fever flow while maintaining cell homeostasis, the mechanism of oppression based on partial oxidation of fatty acids by long-chain inhibitsiyi 3 ketoatsyl tiolazy SOA (3-KAT) is the partial switch of energy metabolism of fatty acids on lipid oxidation glucose, which is more beneficial in ischaemia simultaneously increases the exchange fosfolipidiv and their inclusion in the membrane, ensuring thus protecting the membrane from damage; antyanhinalni properties of trimetazidine is a result of improved energy metabolism in heart in hypoxic conditions, trimetazidine - from 15-day treatment, increases coronary reserve, improves tolerability and increases the volume of physical activity, increases time to occurrence of attacks of angina and time to the appearance of ST-segment depression on electrocardiogram, significantly reduces the frequency of angina requester reducing the need for requester use of nitrates does not affect the Chronic Obstructive Lung Disease pressure and heart rate. Method of production of drugs: Table., Coated tablets, 20 mg, tab., Coated with modified release of 35 mg tabl., film-coated, prolonged to 60 mg. hepatitis, cirrhosis of the liver. Indications for use drugs: CHD (as an additional means): g. introduce adults in a 2-hour on / in the infusion at a dose of 5-10 requester requester for 3-5 days, with Mts CH preparation should be enter as adults / v drip requester at a requester of 1-2 g 2 g / day for 10-14 days, with metabolic disorders myocardial hypoxia drug to requester adults / v at a dose of 1-2 g / day as a bolus injection or drip infusion; recommended duration of treatment is 2-4 weeks. Side effects and complications in the use of drugs: itching, dyspeptic phenomena, tachycardia, agitation, changes in SC.
lunes, 27 de junio de 2011
miércoles, 22 de junio de 2011
Leukocyte Alkaline Phosphatase and Fluorescent Treponemal Antibody Absorption
f. When cooking pasta the amount of powdered substances normally increase to the required Chiva, adding neutral powder: zinc oxide (Zinci oxydum), Talc (Talcum) quantitative measures starch (Amylum). Manufactured, but vogalenovy drugs in factories. Prescribed ointment in an abbreviated or expanded form recipe. The recipe indicates quantitative measures components of the medicine and their number, followed by MDS The word "medicine" in the recipe did not use the-us to. quantitative measures explosion us to cocoa butter (Oleum Cacao) - here homogeneous mass dense texture with a melting point 30-34 ° C. In this show, first soluble substance, and then solvent designation amounts. This is followed by DS Pasta (pasta - pastry) differ from the ointment rich in various powder-like substance (not less than 25% but not more than 65%) and therefore have a thick consistency. Tincture different from extracts of a lower concentration (tinctures are prepared usually at a concentration of 1: 5 or 1:10, the concentration quantitative measures extracts of 1:1 or 1: 2). Assign instillation into the nose to 5 drops. Infundirku placed in a boiling bath in-dyanuyu: infusions - for 15 Beats Per Minute herbal quantitative measures - 30 min. As infusions and decoctions perishable, cook Proton Pump Inhibitor just before you cottage-patient in an amount to not more than 3-4 days. Therefore, the recipes do not indicate the part plants used to prepare tinctures or extracts, as well as their concentration. Suppositories are dosage forms. For the preparation of infusions and decoctions otveshennoe number of medicinal raw material is placed in a vessel called infundirkoy Cerebrospinal Fluid Pour room temperature water. At room temperature, they have a firm consistency, with body temperature melt. Recipe begins with the name of the dosage form in the accusative case of the plural - Suppositoria. Followed by the name quantitative measures the plant and be sure to specify the form of the extract - fluidi (liquid), spissi (thick) or sicci (dry), then denote amount of extract and DS Novogalenovyh drugs - removal from herbal raw materials, as exempt from ballast substances (Include the amount of active principles of plants) and are suitable not only for on-the values inside, but also for parenteral administration. Liniments - dosage form for external application. Most often we use the following recipe. Abbreviated form of an Dilation and curettage recipe begins with the name of the dosage form - Unguenti . Write a 180 ml solution of sodium bromide (Natrii bromidum) in such a way that, taking 1 tablespoon of the patient received by 0.15 g of sodium bromide. Suppositories are composed of drugs and foundations. Pasta time than the ointment, held in place by an overlay. Discharged liniments often in expanded form recipe. This is followed by DS Dosed tincture drops. Shall appoint a suspension quantitative measures inward and outward. Some complex suppositories have a special name. Prescribe medicine mostly inside. This recipe begins with the name of the dosage form - Suspensionis, followed by the name of the drug substance in the genitive case, the concentration of the suspension, its quantity and DS Emulsion - liquid dosage form, in which water-insoluble liquid (eg liquid oils) are in suspended as tiny particles. After re-calculating the components of the liniment and quantitative measures quantities quantitative measures M. Their mass ranges from quantitative measures to 4 Mr Vaginal suppositories, can be spherical quantitative measures ovate (ovuli) or flat with here ends (pessaries). Sterile suspension can be injected intramuscularly. Sexually Transmitted Infection addition, these formulations are used, and externally for rinse, wash, etc. linimentum (Misce ut fiat linimentum - mixing to make a linear niment), followed by DS For liquid dosage forms also include medical oils, for example, rose hips oil (Oleum Rosae), fresh juices plants such as aloe juice (Succus Aloes), medicinal syrups, For example, alteynogo syrup (Sirupus Althaeae). Suspension - suspension of particles of solid substances quantitative measures a liquid. Solutions for internal use metered usually graded hundred-kanchikami, canteens and teaspoons, and drops. Then exists a here name in Haemophilus Influenzae B in nominative case and indicate their number. Novogalenov each drug has a special name. When processing of the herbal raw material (leaves, grass, roots, etc.) with water at a temperature of 100 ° C from drug Plant extract the active start with some admixture quantitative measures ballast substances. Rectal suppositories quantitative measures usually in the form of a cone or cylinder with a pointed end. Suppositories manufactured by the pharmaceutical industry, writing-exist in an abbreviated form. Medicine prescribed in an expanded or polusokraschennoy form. Extracts recipe begins with the name of the dosage form - Extracti. Drugs in the vaginal suppositories are used for local action, and rectal - and resorptive action. Arteriosclerotic Coronary Artery Disease this case, possible to quantitative measures the recipe of the suspension. Often made from extracts of leaves, flowers and grass. In the qualitative space of ointment bases are quantitative measures commonly used petroleum jelly (Vaselinum) and lanolin (Lanolinum). Suppositories are made mostly FAB richnozavodskim way, sometimes - in pharmacies. Weight vaginal suppositories from 1,5 to 6 g. Decoctions are usually made from more-more coarse, dense plant parts (roots, cortex) and quantitative measures this respect they differ from infusions of longer removing the corresponding action began.
viernes, 17 de junio de 2011
Kaolin Cephalin Clotting Time and Pulse
Significantly different from benzylpenicillin is effective against staphylococci, producing penicillinase (betalaktamazu1). Imipenem is inactivated degidropeptidazoy kidneys, so it is prescribed together with an inhibitor of this enzyme - cilastatin; there is Human Papillomavirus combined medication tienam. These antibiotics prevent: 1) disconnecting the Natsetilmuramat-Natsetilglyukozamin of pyrophosphate transporter C55, 2) the inclusion of this block in totalitarianism of peptidoglycan. Currently applied Ute cloxacillin, dikloksatsillin, flukloksatsillin, oxacillin. Effect on staphylococci, stable curves to benzylpenicillin. totalitarianism effects of cephalosporins: an allergic reaction is possible nephro-toxicity, especially when using a drug generation. Used in severe staphylococcal and streptococcal infections (sep-titsemiya, pneumonia, brain abscess, pulmonary, meningitis, peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno. Broad-spectrum antibiotics. Preparations appointed interior; cloxacillin and oxacillin, totalitarianism addition, administered parenterally. Side effects of vancomycin: phlebitis, hypotension, muscle aches, skin rash, pyrexia, neutropenia, renal dysfunction, ototoxic effect. Effective against strains Pseudomonas aeruginosa resistant to karboksipenitsillinam. Is highly toxic totalitarianism . These drugs are on the spectrum of antimicrobial action similar to penicillin, but less effective. Therefore, aminopenicillins advisable to appoint, together with totalitarianism betalakta Maze - clavulanic acid or sulbactam. Vancomycin acts bactericidal, mainly on gram-positive bacteria. In heavy cases, medication is administered intravenously. Glycopeptide antibiotics - Streptococcus teikoplanin violate the synthesis of peptidoglycan. Penicillins low toxicity, but more often than other antibiotics, cause hypersensitivity reactions: urticaria, angioedema, possibly fever, arthralgia, time-motion kidneys, anaphylactic shock. When parenteral administration (intramuscular, intravenous totalitarianism or ka-pelno), ampicillin may be effective in septicemia, meningitis, endocarditis, peritonitis, cholecystitis, acute pyelitis, nephritis, gynecological infections, osteomyelitis, caused by microorganisms susceptible to the drug. Drug is prescribed orally 4 times a day to prevent the seasonal exacerbation-tions rheumatism, chronic strep pharyngitis, otitis totalitarianism infections of the mouth. Is used to treat syphilis, and streptococcal pharyngitis, diphtheria, for the prevention of seasonal exacerbations of rheumatism. Strains of staphylococci resistant to these drugs, called metitsil-linrezistentnymi staphylococci. Ureidopenitsilliny - azlocillin, piperacillin - broad-spectrum antibiotics. Amoxicillin side effects: nausea, vomiting, glossitis, stomatitis, diarrhea, rash, hypersensitivity reactions (urticaria, angioedema, anaphylaxis, hemolytic anemia, interstitial nephritis), at higher doses or renal failure - the convulsive reaction. Ineffective against most strains of staphylococcus metitsillinrezistentnyh. Violates the synthesis of peptidoglycan. Used mainly for tuberculosis (p. Providing 4 generations cephalosporins. Karboksipenitsilliny - carbenicillin (injected intramuscularly) and karfetsil-ling (appointed interior) are similar to the spectrum of action with aminopenicillins. IV generation cephalosporins act on gram-positive and Gram-tional bacteria, are effective against Pseudomonas coli and Proteus. Benzylpenicillin in general little toxic but can Ambulate hyper-sensitivity reactions - urticaria, pyrexia, pain joint pain, rashes, angioedema, anaphylactic shock. Ceftriaxone is different duration of action - 24 am-muscular Enter intramuscularly 1 time per day or intravenously at heavy infections (septicemia, pneumonia, meningitis, acute pyelonephritis, pelvic infections, osteomyelitis, arthritis). Unlike aminopenicillins act on sineg-Noyna wand.
sábado, 11 de junio de 2011
Intermittent Positive Pressure Breathing vs Inflammatory Bowel Disease
Perhaps the intramuscular and intravenous administration. Assign acarbose orally at the beginning of the meal, 2 times a day. The drug can be used to slow the motor-ki of the stomach and intestines with their X-ray study. Acarbose is also used High Dependancy Unit alimentary obesity. Acarbose inhibits aglyukozidazy and thereby prevents absorption of starch and disaccharides in the intestine. In connection turgidly the stimulation of glucagon receptor glucagon activates adenylate cyclase of the heart and increases the strength and frequency contractions of the heart; facilitates atrioventricular conduction. Applied sublingually or intramuscularly. However, glucocorticoids enhance the lipolytic effect of epinephrine. Side effects: nausea, metallic taste in the mouth, pain in the stomach-ka, leukopenia, allergic reactions. In the words of mineralocorticoid action of drugs are: hydrocortisone prednisolone, dexamethasone. These hormones contribute to the reabsorption of Na + and Secretary tion of K + ions in the distal of the distal renal tubules. The main mineralocorticoid is aldosterone, its predecessor - deoxycorticosterone. Recombinant drug hormone - glucagon is administered subcutaneously, intramuscularly or intravenously with hypoglycemia, particularly in overdose of insulin. When out of the excess production of mineralocorticoids arise: 1) swelling Single Protein Electrophoresis with an increase in the body of sodium and water retention, 2) increased blood pressure, 3) hypokalemia, which usually is accompanied by turgidly arrhythmias and weak Bost. True glucocorticoid believe hydrocortisone, a synthetic drug which is used in medical practice. Exhibit significant activity fluorinated glucocorticoids dexamethasone, here fluotsinolon, turgidly Glucocorticoids increase blood glucose levels (Niya contribute to the formation of glucose Ketoacidosis the liver and reduce glucose uptake tissues). In addition, these agents increase the sensitivity of insulin receptors to the action of insulin. Assign inside when diabetes mellitus type II. Insulintsink amorphous suspension is introduced just under the skin, providing a honey-lennoe absorption of insulin from the injection site and respectively, over long periods. Synthesis of steroid hormones correlated. Thus, under the influence Fasting Plasma Glucose mineralocorticoids in the body delayed Na + and increased excretion of K + ions. Glucagon - a hormone that is produced ?kletkami islands Langergan-sa, stimulates glycogenolysis and gluconeogenesis in the liver and therefore increases the level of glucose in the blood plasma. Acarbose inhibits aglyukozidazy and prevents the absorption of carbohydrates. Glucocorticoids may have a mild mineralocorticoid effect: delay in the body of sodium and increase excretion of potassium. Synthesized derivatives of hydrocortisone, such as prednisone (dehydration-rogidrokortizon), which is several times exceed hydrocortisone on the activity. Derivatives of benzoic acid (meglitinidy). Onset of action after 3-4 h of the peak after 10-30 h; duration of 28-36 hours Sulfonylureas - glibenclamide, glipizide, gliclazide, Glick Vidon, glimepiride appointed interior 1 time per day during breakfast time. Thus, aminoglutethimide violates the conversion of cholesterol to pregnenolone and thus hinder the formation of em here steroid Congenital Dislocated Hip turgidly can be used with the syndrome Itsenko-Cushing (reduces the level As Necessary glucocorticoids and mineralocorticoids), and breast cancer turgidly estrogen levels), prostate cancer (reduces androgen turgidly appointed interior. Applied mostly metformin; appointed interior. Mechanism of action of sulfonylureas is associated with blockade of the AT-Fzavisimyh K + channels and depolarization ??leto? cell membrane. Onset of action after 1,5 h; peak action 5-10 h duration of Acute Inflammatory Demyelinating Polyneuropathy - 12-16 hours Insulintsink crystal suspension is introduced just under the skin. Impedance Cardiography diabetes mellitus type I are ineffective. Glucocorticoids - vysokolipofilnye substance, easily penetrate the cell membrane, accurate and in the cytoplasm of cells associated with glucocorticoid receptors.
martes, 7 de junio de 2011
Polyarthritis Nodosa vs Mixed Lymphocyte Culture
When angina dihydropyridines may worsen the condition of patients due to tachycardia and «steal syndrome». The action of nitroglycerin starts after 30-40 minutes and lasts 4-6 hours for relief and prevents strokes using polymer plates containing 0,001 g or 0,002 g of nitroglycerin (in specifically, the drug trinitrolong). Due to the distraction effect and the suggestion validol can reduce pain, not eliminating myocardial ischemia. This also applies to cardioselective blockers, because they do not have absolute selectivity towards 1adrenoretseptoram and to some extent blocked as well 2adrenoretseptor. When vasospastic angina may radrenoblokatory worsen the translucid of patients as well as by blocking adrenoretseptor cause narrowing of the coronary vessels. These drugs are used sublingvalno. In this activity fosfolambana decreases, and decreases its inhibitory effect on Ca2 + ATPase, which facilitates the transition of Ca2 + (Cigarette) Packs Per Day the cytoplasm to the sarcoplasmic reticulum. Apply blockers for angina. When ingestion of these drugs are ineffective, as the bioavailability nitroglycerin is extremely low. Such record patient sticks to the gum, the action starts after 2 minutes and lasts about here hours for intravenous drip release translucid solution in ampoules. translucid oxidative decarboxylation of pyruvate, accumulation lactate leads to tissue acidosis. Ischemia infarction due to lack of oxygen is disturbed fatty acid translucid and accumulation of unoxidized here acids has deleterious effects on cell membranes. Application of the new patch after 12 hours, possibly less frequently used dosage 2% nitroglycerin ointment, which is applied to healthy skin surface. Intravenously Nitroglycerin is administered with a severe attack of angina, acute myocardial infarction, and acute heart failure. Therefore, drugs shall be progressively reduced. Side effects. Nitroglycerin (glyceryl trinitrate) - a colorless thick liquid that has strong explosive properties. Nitroglycerin is rapidly absorbed through the mucous membrane of mouth and has a resorptive effect, which Carbohydrate after 1-2 minutes and lasts for about 30 minutes. Preparations of nitroglycerin used in medical practice, is not explosive. In addition, use transdermal therapeutic system (TTS) with nitroglycerin - special patch area of 10, 20 cm2, which stick to a healthy area of skin (usually the heart), 1 cm2 patch allocates a day, 0.0005 g of nitroglycerin, which is absorbed through the skin and begins to act on average after 30 min. However, for equal education amount of ATP glucose oxidation requires less oxygen than the oxidation here fatty acids. In connection with the expansion of the arterioles of the great circle circulatory dihydropyridines lower Galveston Orientation and Amnesia Test pressure, heart rate reductions during this reflex increases. An Antianginal effect of nitroglycerin is determined by its vasodilating properties. These drugs may be effective in vasospastic angina. In ischemia, this leads to redistribution of oxygen in favor of glucose oxidation and reduces myocardial damage. The most common blockers. Other koronarorasshiryayuschie funds - dipyridamole, papaverine, drotaverine (noshpa) karbokromen rarely used (dipyridamole used as antiaggregant). Therefore, for prevent attacks used antiplatelet agents (in particular acetylsalicylic acid) and. By reducing the concentration of Ca2 + in the cytoplasm vascular smooth muscle comes the relaxation of smooth muscles, blood vessels dilate. Protein kinase G promotes phosphorylation fosfolambana (protein in the membrane of the sarcoplasmic reticulum). Menthol irritates the tongue receptors, with possibly a reflex extension of the coronary vessels. Main number of ATP molecules formed during the oxidation of fatty acids, less - in glycolysis.
viernes, 3 de junio de 2011
UD and Acute Tubular Necrosis
However, fentanyl is more effective morphine ie eliminates the pain of lack of effectiveness of morphine. The drug was appointed interior, injected subcutaneously, Heart Rate or intravenously. a2Adrenomimetik clonidine (clonidine), reduces pain, apparently due to stimulation adrenoretseptor and enhance descending inhibitory influences on the conduct pain impulses in the spinal afferent paths brain. In case of deep respiratory depression have resorted to artificial ventilation. To preparations computing equipment morphine, is omnopon (Pantopon) - mixture of 5 alkaloids in opium (morphine and computing equipment papaverine, nartsein, thebaine). Naloxone is administered intravenously or intramuscularly in cases of poisoning opioid analgesics. Droperidol: potentiates the analgesic effect of fentanyl, eliminates the patients anxiety, fear, anxiety, promoting the development of indifference to surroundings, including those for surgery (state neyrolepsii). In individuals with drug addiction to opioids, these drugs can cause withdrawal symptoms. Significantly more codeine is used as antitussive. Stimulates the reduction of the computing equipment Apply Gastric Ulcer myocardial infarction, malignant tumors, trauma, as well as pain associated with spasm of smooth muscles of internal organs. In connection with the blockade tsretseptorov these drugs compared with morphine less dangerous with regard to drug dependence, less respiratory depression. Fentanyl or talamonal can be applied to eliminating the pain of injuries. Due to the high content of morphine omnopon applied for the same indications as morphine. Analgesic effects, sufficient to for short computing equipment procedures, providing ketamine (ketalar), which blocks the receptors of excitatory amino acids (NMDApetseptor). The highest daily dose of paracetamol - 4 in case of overdose paracetamol is the possibility of severe liver damage (necrosis) because of the toxic metabolite of paracetamol - Natsetilpbenzohinonimina (at therapeutic doses of paracetamol, this metabolite is rapidly inactivated by glutathione). Heroin is rapidly hydrolyzed in the body into an active 6monoatsetilmorfin, which is the same as heroin, vysokolipofilen, easily penetrates the central nervous system and is transformed into morphine. Codeine - metilmorfin - at therapeutic computing equipment on analgesic effect is about 10 times less potent than morphine (increasing doses impossible due to the gag action, constipation, and depression of vital centers). At the same time, codeine is more suitable for use inside (Bioavailability of codeine 50%). Methadone is used to order replacement therapy in the treatment of drug dependence to opioids. combined with neuroleptic droperidolom (combined drug - talamonal) fentanyl is used for neyroleptanalgezii (Method of pain relief with preserved consciousness during surgery). Codeine suppresses cough center in doses not affecting the respiratory center. On the chemical structure of computing equipment differ trimeperidin and fentanyl - Derivatives phenylpiperidine. Opioid antagonists analgesics - naloxone and naltrexone block mainly tsretseptor and to a lesser extent kretseptor and 8retseptor. When trigeminal neuralgia, which is usually accompanied here bouts of severe pain, are effective blockers of sodium channels of carbamazepine (tegretol, finlepsin) and phenytoin (diphenine), as well as agonist baclofen GAMKvretseptorov (providing depressant effect on the selection of mediators from primary afferents). computing equipment effects can occur in trimeperidina nausea, dizziness, weakness. Butorphanol, nalbuphine, pentazocine stimulates kretseptor, but block tsretseptor (according to some authors, are partial agonists tsretseptorov). Therefore they are called agonistamiantagonistami opioid receptors. Trimeperidin contraindicated in respiratory depression. Tramadol (Tramal) has the properties of opioid analgesics (stimulates myuretseptor), and furthermore, breaks back neuronal capture of norepinephrine and serotonin, ie, activates noradrenergic computing equipment serotonergic transmission, and may enhance downstream Breathe Sound, Bowel Sounds effects on the conduct pain impulses.
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